Bhavana Bhatnagar, Qiuhong Zhao, James L. Fisher, et al.
Conclusion: Self-reported AA race is the most important pt-associated factor associated with poor survival in AML pts < 60 y of age based on SEER. Survival analyses in Alliance pts identify AA race as independent poor survival prognosticator in AML pts besides established molecular markers. . This disparity must be urgently addressed to ensure improved outcomes for AA AML pts, and larger studies to establish molecular risk profiles are needed.
Lana Mucalo, Amanda M. Brandow, Sadie F. Mason, et al.
Conclusion: The findings show that individuals with SCD who have COVID-19 infection have higher rates of death due to COVID-19 than the general Black population. Also, a large proportion of COVID hospitalization for the SCD population occurs among the younger age group. Further analysis is planned to examine effects of underlying comorbidities and prior SCD-associated complications on the severity of COVID-19 in individuals with SCD.
302 COVID-19 Outcomes in Individuals with Sickle Cell Disease and Sickle Cell Trait Compared to Blacks without Sickle Cell Disease or Trait according to ASH clinically relevant abstract
Ashima Singh, Amanda M. Brandow, and Julie Panepinto.
Conclusions: These data provide evidence that sickle cell disease imposes additional risk of severe COVID-19 illness and hospitalization, after balancing for age, gender and other preexisting conditions. The death rate between sickle cell disease and Blacks without sickle cell trait/disease was not significantly different. There are no significant differences in COVID-19 outcomes between sickle cell trait and Blacks without sickle cell trait/disease, after balancing for age, gender and other pre-existing conditions.