Startseite Kongressberichte & Archiv All-Virtual 62nd ASH Annual Meeting and Exposition Press Briefings Press Briefing on Disparities in Health Care: Diversity, Equity, and Inclusion (DEI)

Disparities in Health Care: Diversity, Equity, and Inclusion (DEI) (Moderator - Chancellor Donald, MD, Tulane University)

Disparities in Health Care: Diversity, Equity, and Inclusion (DEI) press release

Abstracts presented:

6 Poor Treatment Outcomes of Young (<60 Years) African American Patients (Pts) Diagnosed with Acute Myeloid Leukemia (AML) (Alliance)

Bhavana Bhatnagar, Qiuhong Zhao, James L. Fisher, et al.

Conclusion: Self-reported AA race is the most important pt-associated factor associated with poor survival in AML pts < 60 y of age based on SEER. Survival analyses in Alliance pts identify AA race as independent poor survival prognosticator in AML pts besides established molecular markers. . This disparity must be urgently addressed to ensure improved outcomes for AA AML pts, and larger studies to establish molecular risk profiles are needed.

217 The Role of Structural Violence in Acute Myeloid Leukemia Outcomes

Ivy Abraham, Garth Rauscher, Anand Ashwin Patel, et al. & Irum Khan
Discussion: This study is the first to integrate data at the individual patient level with neighborhood characteristics, using census tract level variables to examine their contribution to AML patient outcomes. To date, formal mediation methods had not been employed to disentangle race/ethnic disparities in adult AML survival. Notably, our mediation analysis shows that census tract level SES explains a substantial proportion of the disparity in hazard of leukemia death. In addition, the observed disparities in treatment complications of induction chemotherapy, as reflected by ICU admissions, and the continued disparity in allogeneic transplant utilization all warrant further study. These results draw attention to the need for deeper investigation into the social and economic barriers to successful treatment outcomes for leukemia patients and represent an important first step toward designing strategies to mitigate these persistent health inequities.

16 Hospitalization and Case Fatality in Individuals with Sickle Cell Disease and COVID-19 Infection

Lana Mucalo, Amanda M. Brandow, Sadie F. Mason, et al.

Conclusion: The findings show that individuals with SCD who have COVID-19 infection have higher rates of death due to COVID-19 than the general Black population. Also, a large proportion of COVID hospitalization for the SCD population occurs among the younger age group. Further analysis is planned to examine effects of underlying comorbidities and prior SCD-associated complications on the severity of COVID-19 in individuals with SCD.

302 COVID-19 Outcomes in Individuals with Sickle Cell Disease and Sickle Cell Trait Compared to Blacks without Sickle Cell Disease or Trait according to ASH clinically relevant abstract

Ashima Singh, Amanda M. Brandow, and Julie Panepinto.

Conclusions: These data provide evidence that sickle cell disease imposes additional risk of severe COVID-19 illness and hospitalization, after balancing for age, gender and other preexisting conditions. The death rate between sickle cell disease and Blacks without sickle cell trait/disease was not significantly different. There are no significant differences in COVID-19 outcomes between sickle cell trait and Blacks without sickle cell trait/disease, after balancing for age, gender and other pre-existing conditions.